Table S12 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Asael Roichman; Gabriela Reyes‐Castellanos; Ziqing Chen; Zihong Chen; Sarah J. Mitchell; Michael R. MacArthur; Akshada Sawant; Llewelyn Levett; Jesse R. Powers; Victoria Burgo; Maria Gomez-Jenkins; Maria Ibrahim; Xincheng Xu; Beianka Tomlinson; Xiang Hang; Eric G. Pamer; Yong Wei; Yibin Kang; Eileen White; Joshua D. Rabinowitz

doi:10.1158/0008-5472.30029857

Key Points

Dietary fiber shows varying effects on immune checkpoint blockade efficacy, suggesting inconsistent impact across murine models.
In tumor immune profiling using flow cytometry, immune responses dramatically differed, emphasizing the complexity of dietary interventions.
The study involved diverse murine tumor models to assess the relationship between dietary fiber and immune checkpoint responses.
Findings may influence future research on dietary fiber, immune therapy strategies, and personalized cancer treatment approaches.

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Implication

Analysis reveals inconsistent effects of dietary fiber on immune checkpoint blockade efficacy in murine tumor models, highlighting the need for deeper investigation.

Abstract

Tumor immune profiling in the PyMT model by flow cytometry

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Roichman et al. (2025) studied this question.

synapsesocial.com/papers/68bb4e016d6d5674bcd02b02 https://doi.org/10.1158/0008-5472.30029857

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Table S12 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Table S12 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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