Table S7 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Asael Roichman; Gabriela Reyes‐Castellanos; Ziqing Chen; Zihong Chen; Sarah J. Mitchell; Michael R. MacArthur; Akshada Sawant; Llewelyn Levett; Jesse R. Powers; Victoria Burgo; Maria Gomez-Jenkins; Maria Ibrahim; Xincheng Xu; Beianka Tomlinson; Xiang Hang; Eric G. Pamer; Yong Wei; Yibin Kang; Eileen White; Joshua D. Rabinowitz

doi:10.1158/0008-5472.30029839

Key Points

The findings indicate that dietary fiber does not consistently enhance immune checkpoint blockade efficacy in murine tumor models.
Notably, variations in serum metabolite peak areas were observed within the PyMT model across different tumor types.
This research involves an observational analysis across diverse murine tumor models to understand dietary fiber's impact.
The results highlight the need for further studies to clarify dietary fiber's role in cancer treatment efficacy.

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Implication

Observational analysis shows inconsistent effects of dietary fiber on immune checkpoint blockade efficacy across diverse murine tumor models, suggesting varied responses.

Abstract

Serum metabolite peak areas from the PyMT model

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Roichman et al. (2025) studied this question.

synapsesocial.com/papers/68bb5f076d6d5674bcd02b3a https://doi.org/10.1158/0008-5472.30029839

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Table S7 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Table S7 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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