Table S12 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Asael Roichman; Gabriela Reyes‐Castellanos; Ziqing Chen; Zihong Chen; Sarah J. Mitchell; Michael R. MacArthur; Akshada Sawant; Llewelyn Levett; Jesse R. Powers; Victoria Burgo; Maria Gomez-Jenkins; Maria Ibrahim; Xincheng Xu; Beianka Tomlinson; Xiang Hang; Eric G. Pamer; Yong Wei; Yibin Kang; Eileen White; Joshua D. Rabinowitz

doi:10.1158/0008-5472.30210044

Key Points

Dietary fiber's influence on immune checkpoint blockade efficacy varies significantly across tumor models.
The study involved tumor immune profiling utilizing flow cytometry in the PyMT model, revealing inconsistent results.
Assessment focused on murine tumor models to determine the impact of dietary fiber on treatment responses.
Findings highlight the need for further investigation into the role of dietary fiber in cancer immunotherapy effectiveness.

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Implication

Observational analysis indicates that dietary fiber may not consistently enhance immune checkpoint blockade efficacy across various murine tumor models.

Abstract

Tumor immune profiling in the PyMT model by flow cytometry

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Cite This Study

Roichman et al. (2025) studied this question.

synapsesocial.com/papers/68d7b3ddeebfec0fc52366d7 https://doi.org/10.1158/0008-5472.30210044

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Table S12 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Table S12 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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