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September 2, 2025Open Access

Table S2 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Asael Roichman Gabriela Reyes‐Castellanos Ziqing Chen Zihong Chen Sarah J. Mitchell Michael R. MacArthur Akshada Sawant Llewelyn Levett Jesse R. Powers Victoria Burgo Maria Gomez-Jenkins Maria Ibrahim Xincheng Xu Beianka Tomlinson Xiang Hang Eric G. Pamer Yong Wei Yibin Kang Eileen White Joshua D. Rabinowitz

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Key Points

Dietary fiber does not show a consistent effect on immune checkpoint blockade efficacy.
The analysis reveals that the impact varies across diverse murine tumor models, with some showing negligible responses.
Flow cytometry was used to assess immune responses, providing insights into the interaction between dietary components and immune therapies.
These findings suggest the need for tailored dietary strategies in cancer immunotherapy based on tumor type.

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Implication

Analysis shows variable efficacy of dietary fiber on immune checkpoint blockade, highlighting its inconsistent effects across murine tumor models.

Abstract

Antibodies used for flow cytometry

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Cite This Study

Roichman et al. (2025) studied this question.

synapsesocial.com/papers/68bb5f076d6d5674bcd02b49 https://doi.org/10.1158/0008-5472.30029854

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Table S2 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models2025
2Table S2 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models2025
3Figure S1 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models2025
4Table S12 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models2025
5Table S12 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models2025

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