Figure S1 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Q: What type of study is this?

This is a Cross-Sectional Study study.

Asael Roichman; Gabriela Reyes‐Castellanos; Ziqing Chen; Zihong Chen; Sarah J. Mitchell; Michael R. MacArthur; Akshada Sawant; Llewelyn Levett; Jesse R. Powers; Victoria Burgo; Maria Gomez-Jenkins; Maria Ibrahim; Xincheng Xu; Beianka Tomlinson; Xiang Hang; Eric G. Pamer; Yong Wei; Yibin Kang; Eileen White; Joshua D. Rabinowitz

doi:10.1158/0008-5472.30210074

Key Points

Dietary fiber showed no consistent effect on immune checkpoint blockade efficacy in tumor models, indicating potential variability.
Analysis included various murine tumor models, confirming that dietary fiber's role is unpredictable in immune responses.
Flow cytometry was employed to assess immune cell populations, aiding in understanding the interaction with dietary fiber.
These findings highlight the need for further investigation to understand the underlying mechanisms affecting treatment efficacy.

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Implication

Analysis reveals dietary fiber lacks consistent effects on immune checkpoint blockade efficacy across murine tumor models, suggesting variability in impact.

Abstract

Flow cytometry gating strategy

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Cite This Study

Roichman et al. (2025) studied this question.

synapsesocial.com/papers/68d7b3ddeebfec0fc52366cc https://doi.org/10.1158/0008-5472.30210074

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Figure S1 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Figure S1 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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