Table S2 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Q: What type of study is this?

This is a Experimental Study study.

Asael Roichman; Gabriela Reyes‐Castellanos; Ziqing Chen; Zihong Chen; Sarah J. Mitchell; Michael R. MacArthur; Akshada Sawant; Llewelyn Levett; Jesse R. Powers; Victoria Burgo; Maria Gomez-Jenkins; Maria Ibrahim; Xincheng Xu; Beianka Tomlinson; Xiang Hang; Eric G. Pamer; Yong Wei; Yibin Kang; Eileen White; Joshua D. Rabinowitz

doi:10.1158/0008-5472.30210041

Key Points

Dietary fiber does not consistently influence immune checkpoint blockade efficacy in various tumor models, indicating a nuanced relationship.
Key findings reveal that the addition of dietary fiber had varied effects across different murine tumor models, making generalizations difficult.
Analysis involved multiple tumor models and assessed immune response differences due to dietary fiber, highlighting complexity in interactions.
Findings call for further exploration of dietary components in relation to immune therapies, particularly regarding tumor response.

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Implication

Observational analysis shows dietary fiber lacks consistent impact on immune checkpoint blockade efficacy across diverse murine tumor models, suggesting further investigation is needed.

Abstract

Antibodies used for flow cytometry

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Cite This Study

Roichman et al. (2025) studied this question.

synapsesocial.com/papers/68d7b3ddeebfec0fc52366f4 https://doi.org/10.1158/0008-5472.30210041

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Table S2 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Table S2 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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