Supplemental Table S2 from Cytotoxic NK Cells Impede Response to Checkpoint Immunotherapy in Melanoma with an Immune-Excluded Phenotype

Key Points

• Cytotoxic NK cells significantly impede response to checkpoint immunotherapy in melanoma, affecting treatment efficacy.
• Initial immune cell clusters reveal discriminatory marker genes that influence immunotherapy outcomes.
• Research employs analysis of immune cell clusters to uncover interactions with checkpoint immunotherapy.
• Understanding these mechanisms may highlight crucial therapeutic avenues for improving immunotherapy in melanoma.