Table S2 from TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing Sarcoma

Jessica D. Daley; Elina Mukherjee; David Ferraro; A. Carolina Tufino; Nathanael G. Bailey; Shanthi Bhaskar; Nivitha Periyapatna; Ian MacFawn; Sean Hartwick; Sheryl Kunning; Cynthia S. Hinck; Tullia C. Bruno; Adam C. Olson; Linda M. McAllister‐Lucas; Andrew P. Hinck; Kristine Cooper; Riyue Bao; Anthony R. Cillo; Kelly M. Bailey

doi:10.1158/2767-9764.29992545

Key Points

Inhibition of tgfβ during radiotherapy results in decreased metastases in Ewing Sarcoma.
This approach enhances immune cell infiltration, indicating potential for improved therapeutic outcomes.
The method involved radiotherapy combined with tgfβ inhibition, demonstrating significant changes in tumor behavior.
These findings may support further studies on tgfβ inhibition in Ewing Sarcoma and similar cancers.

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Implication

Ewing Sarcoma treatment shows enhanced immune cell infiltration and reduced metastases with tgfβ inhibition, suggesting promising therapeutic applications.

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Daley et al. (2025) studied this question.

synapsesocial.com/papers/68c1d24654b1d3bfb60f84f8 https://doi.org/10.1158/2767-9764.29992545

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Table S2 from TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing Sarcoma

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Table S2 from TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing Sarcoma

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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