Figure S14 from TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing Sarcoma

This is a In Vitro Study study.

Key Points

Inhibition of TGFβ increased immune cell infiltration and decreased metastases in Ewing sarcoma.
The TC32 Ewing sarcoma cell line showed increased sensitivity to radiation therapy compared to A673.
Assessment using the TC32 and A673 cell lines shows significant differences in response to radiation.
Highlights the potential for TGFβ inhibition to improve radiotherapy outcomes in Ewing sarcoma.

Inhibition of TGFβ enhances immune cell infiltration and reduces metastases in Ewing sarcoma cell lines, suggesting a novel therapeutic strategy.

Figure S14. The TC32 EwS cell line demonstrates increased sensitivity to radiation therapy compared to the A673 cell line in vitro.

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Daley et al. (2025) studied this question.

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