Figure 3 from Mesenchymal Stem Cells Expressing CES1 and Soluble TRAIL Activate CPT-11 and Induce Apoptosis in Lung Cancer Brain Metastatic Lesions

Modeling lung cancer brain metastasis using NSCLC. A and B, Tumor growth was monitored with luciferase expression via IVIS Spectrum imaging at different time points, and mice were imaged 10 minutes after luciferin intraperitoneal injection. C and D, Changes in mouse body weight after NSCLC injection. E and F, Plot of bioluminescence signal changes showing in vivo tumor growth. G, Histologic analysis of tumor tissues included hematoxylin and eosin (H&E) and Ki67 staining. Scale bar, 100 μm. All results are expressed as the mean ± SD.