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October 2, 2025Open Access

Supplementary Figure S7 from Functional Analysis of Rare RAS Variants of Unknown Significance

Soohwan Park Masachika Ikegami Rina Kitada Kazuya Takamochi Kenji Suzuki Hiroyuki Mano Shinji Kohsaka

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Key Points

Proliferative capacity of KRAS variants shows significant variation in co-culture assays, influencing therapeutic strategies.
The study assesses multiple KRAS variants in a co-culture setting, highlighting their potential roles in oncogenesis.
This investigation uses a co-culture assay to evaluate the effects of KRAS variants on cell growth and interaction.
Findings underscore the importance of characterizing KRAS variants, calling for deeper exploration into their functional roles.

Implication

Analysis reveals proliferative capacity of KRAS variants in co-culture assays, indicating their biological significance.

Abstract

Proliferative capacity of KRAS variants in the co-culture assay

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Cite This Study

Park et al. (2025) studied this question.

synapsesocial.com/papers/68de6f3f83cbc991d0a22d22 https://doi.org/10.1158/2767-9764.30261464

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S9 from Functional Analysis of Rare <i>RAS</i> Variants of Unknown Significance2025
2Supplementary Figure S8 from Functional Analysis of Rare <i>RAS</i> Variants of Unknown Significance2025
3Supplementary Figure S4 from Functional Analysis of Rare <i>RAS</i> Variants of Unknown Significance2025
4Supplementary Figure S2 from Functional Analysis of Rare <i>RAS</i> Variants of Unknown Significance2025
5Supplementary Figure S1 from Functional Analysis of Rare <i>RAS</i> Variants of Unknown Significance2025