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October 2, 2025Open Access

Supplementary Figure S1 from Functional Analysis of Rare RAS Variants of Unknown Significance

Soohwan Park Masachika Ikegami Rina Kitada Kazuya Takamochi Kenji Suzuki Hiroyuki Mano Shinji Kohsaka

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Key Points

The variant assessment schema outlines the functional testing methods used to evaluate RAS variants.
This assessment focuses on identifying the biological significance of RAS variants classified as unknown significance.
Functional analysis employs specific assays designed to elucidate the roles of these rare genetic variants.
Understanding these variants may provide insights into their implications for genetic disorders.

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Implication

Assessment evaluates functional implications of rare RAS variants, indicating biological relevance.

Abstract

Schema of the assays for the variant assessment

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Cite This Study

Park et al. (2025) studied this question.

synapsesocial.com/papers/68de6f3f83cbc991d0a22d41 https://doi.org/10.1158/2767-9764.30261482

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S4 from Functional Analysis of Rare <i>RAS</i> Variants of Unknown Significance2025
2Supplementary Figure S2 from Functional Analysis of Rare <i>RAS</i> Variants of Unknown Significance2025
3Supplementary Figure S6 from Functional Analysis of Rare <i>RAS</i> Variants of Unknown Significance2025
4Supplementary Figure S9 from Functional Analysis of Rare <i>RAS</i> Variants of Unknown Significance2025
5Supplementary Figure S7 from Functional Analysis of Rare <i>RAS</i> Variants of Unknown Significance2025