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September 4, 2024Advances in Human BiologyOpen Access

Evaluating the Clinico-biochemical Association between Stress and Chronic Periodontitis by Estimation of Serum Cortisol and Serum Chromogranin A Levels

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Authors

SDShilpa DusejaManubhai Patel Dental College and HospitalHPHiral Akshat ParikhManubhai Patel Dental College and HospitalSDSareen DusejaManubhai Patel Dental College and Hospital

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Implication

Observational study reveals elevated serum cortisol and chromogranin A in chronic periodontitis, indicating that psychological stress acts as a periodontal risk factor.

Key Points

  • Serum cortisol and serum chromogranin a levels are significantly elevated in chronic periodontitis compared with healthy controls (P ≤ 0.05).
  • Assessment of 400 systemically healthy participants evaluated clinical attachment loss and psychoneuroimmunologic variables using structured stress scales.
  • Psychological stress links to chronic periodontitis severity, suggesting stress reduction strategies may benefit patients facing unexplained periodontal breakdown.

Cite This Study

Duseja et al. (2024) studied this question.

synapsesocial.com/papers/68e5955bb6db6435875305f8https://doi.org/10.4103/aihb.aihb_58_23
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Review of Biophysiological and Biochemical Indicators of Stress for Connected and Preventive Healthcare2021 · 52 citations
  2. 2Effect of stress, depression, and anxiety over periodontal health indicators among health professional students2019 · 16 citations
  3. 3Chronic stress accelerates ligature-induced periodontitis by suppressing glucocorticoid receptor-α signaling2016 · 32 citations
  4. 4The relationship of stress and anxiety with chronic periodontitis2003 · 147 citations