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October 15, 2025Open Access

Supplementary Figure S9 from Resilience and Vulnerabilities of Tumor Cells under Purine Shortage Stress

Jianpeng Yu Chen Jin Cheng Su David Moon Michael A. Sun Hong Zhang Xue Jiang Fan Zhang Nomingerel Tserentsoodol Michelle Bowie Christopher J. Pirozzi Daniel J. George Robert Wild Xia Gao David M. Ashley Yiping He Jiaoti Huang

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Key Points

Tumor cells demonstrate resilience while facing purine shortage stress, adapting through various strategies.
Key vulnerabilities were identified in tumor cells under purine shortage conditions, revealing critical stress points.
The graphical abstract visually summarizes these adaptation strategies and highlights the vulnerabilities of tumor cells.
Understanding these stresses and vulnerabilities could enhance treatment strategies targeting tumor cells.

Implication

Graphical abstract highlights tumor cells' vulnerabilities and adaptation strategies under purine shortage stress.

Abstract

A graphical abstract summarizing tumor cells’ strategies for adapting to and their vulnerabilities under purine shortage stress.

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Cite This Study

Yu et al. (2025) studied this question.

synapsesocial.com/papers/68f199c5de32064e504dcd9a https://doi.org/10.1158/1078-0432.30363226

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S5 from Resilience and Vulnerabilities of Tumor Cells under Purine Shortage Stress2025
2Supplementary Figure S2 from Resilience and Vulnerabilities of Tumor Cells under Purine Shortage Stress2025
3Supplementary Figure S4 from Resilience and Vulnerabilities of Tumor Cells under Purine Shortage Stress2025
4Supplementary Figure S3 from Resilience and Vulnerabilities of Tumor Cells under Purine Shortage Stress2025
5Supplementary Figure S6 from Resilience and Vulnerabilities of Tumor Cells under Purine Shortage Stress2025

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Supplementary Figure S1 from Resilience and Vulnerabilities of Tumor Cells under Purine Shortage Stress2025
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Data from Resilience and Vulnerabilities of Tumor Cells under Purine Shortage Stress2025