Analysis shows significant association of rs9461276 alleles with tRNA-derived fragment expression in CRC tissues, suggesting potential cancer risk implications.
Figure S5. The association between the alleles of rs9461276 and the expression levels of tRF-18-HSQS52D2 in the matched normal tissues from our own CRC samples. tRFQTL rs9461276 is significantly associated with tRF-18-HSQS52D2 expression in the matched normal tissues from our own CRC samples. The expression levels of tRF-18-HSQS52D2 were quantified using qRT-PCR and were normalized to that of U6. Data are shown as the median (minimum to maximum). The P-value was calculated using a linear regression analysis.
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Li et al. (2025) studied this question.
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