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October 18, 2025Journal of Cosmetic DermatologyOpen Access

Bio‐Revitalizing SkinGlow: Assessing the Efficacy of Microcannula‐Assisted Treatment With Cohesive Polydensified Matrix Hyaluronic Acid With Glycerol (Belotero Revive) Through Ultrasound Elastography and Corneometry

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Authors

SLStélio Pacca Loureiro Luna

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Overview

Retrospective cohort study shows significant improvement in skin hydration using hyaluronic acid, indicating a new approach in aesthetic dermatology.

Key Points

  • Hydration significantly improved by 14.9% after one treatment and 16.6% after two treatments.
  • All patients reported improved facial appearance, either ‘much improved’ or ‘very much improved’ after treatment.
  • Among 40 patients, 75% reported minimal discomfort, with an average VAS pain score of 1 out of 10.
  • No serious adverse events were recorded, indicating high safety and tolerability of the procedure.

Cite This Study

Stélio Pacca Loureiro Luna (2025) studied this question.

synapsesocial.com/papers/68f35bfc73f0a7d050f47e64https://doi.org/10.1111/jocd.70509
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Facial Skin Revitalization With <scp>CPM</scp> ‐ <scp>HA20G</scp> (Hyaluronic Acid + Glycerol): A Comparative Case Series Using Three Delivery Techniques With Ultrasound Confirmation2026
  2. 2Efficacy and Safety of Non-cross-Linked Hyaluronic Acid Injections for Facial Skin Biorevitalization: A Single-Center, Open-Label, Single-Arm, Uncontrolled, Post-marketing Study2025 · 6 citations
  3. 3Evaluating Efficacy and Tolerability of a New Intradermal Biorejuvenation with Free Hyaluronic Acid and Glycerol in Photoaging: A Retrospective Pilot Study2025
  4. 4Hybrid Calcium Hydroxylapatite–Polynucleotide Skin Booster A Retrospective Cohort Study2026
  5. 5Reviving the Skin From Within: Mechanistic Insights Into a Well‐Tolerated Dermal Filler— <scp>CPM</scp> ‐ <scp>HA20G</scp>2026