Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2025BloodOpen Access

Impact of obesity on inpatient outcomes in patients hospitalized with acute chest syndrome

View Full Paper
Ask AI
Bookmark
Share

Authors

AAAbdulmalek AljafariAHAdnan Humam HajjarMPMayank Patel

Discussion

Loading...

Member takes

Overview

Retrospective analysis shows obesity increases needs for mechanical and non-invasive ventilation in acute chest syndrome, indicating respiratory risks.

Key Points

  • This research evaluates how obesity affects inpatient mortality and respiratory support needs in acute chest syndrome.
  • Conducted a retrospective analysis using National Inpatient Sample data from 2016 to 2022.
  • Identified patients using ICD-10-CM codes for acute chest syndrome and obesity.
  • Analyzed outcomes including mortality, length of stay, charges, and ventilation needs using logistic and linear regression.
  • 6.4% of patients hospitalized with ACS had obesity.
  • Obese patients required mechanical ventilation 44% more often and non-invasive ventilation 300% more often than non-obese patients.
  • Adjusted analyses showed no significant association between obesity and inpatient mortality or length of stay.

Cite This Study

Aljafari et al. (2025) studied this question.

synapsesocial.com/papers/69362f5a4fa91c937236dadbhttps://doi.org/10.1182/blood-2025-4727
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Outcomes of overweight and obese critically ill patients with severe acute respiratory infection2025
  2. 2Association of obesity and mortality in patients with COVID-19 acute respiratory distress syndrome: A retrospective cohort study2024
  3. 3Body mass index and critical care outcomes in hospitalized COVID-19 patients—A national cohort study2025
  4. 4Effect of obesity on intensive care morbidity and mortality: A meta-analysis*2008 · 506 citations
  5. 5Obesity and Long‐Term Clinical and Economic Outcomes in Coronary Artery Disease Patients2002 · 54 citations