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December 1, 2025Journal of Cystic FibrosisOpen Access

Heterogeneous use of multiple breath washout in cystic fibrosis across age groups and European countries: an ECFSPR analysis

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Authors

AZAnna ZolinSGSimone GambazzaALAnders Lindblad

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Overview

Retrospective analysis highlights age group disparities in lung function assessment of pediatric cystic fibrosis patients across Europe.

Key Points

  • Overall, 10% of people with cystic fibrosis had a multiple breath washout measurement in 2023 across 22 countries.
  • Among the pediatric age groups, 23% of children aged 6-11 and 12-17 years underwent MBW assessments in 2023.
  • Data analytics from the European Cystic Fibrosis Society Patient Registry included 39,986 non-transplanted pediatric and adult participants.
  • The study calls for standardized MBW devices and data protocols to improve lung function measurement accuracy in cystic fibrosis care.

Cite This Study

Zolin et al. (2025) studied this question.

synapsesocial.com/papers/69402a6b2d562116f2901bc5https://doi.org/10.1016/j.jcf.2025.12.001
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ERS technical standard: Global Lung Function Initiative reference values for multiple breath washout indices2024 · 38 citations
  2. 2Silence of the lungs: comparing measures of slow and non-communicating lung units from pulmonary function tests with computed tomography2024 · 6 citations
  3. 3Simultaneous sulfur hexafluoride and nitrogen multiple-breath washout (MBW) to examine inherent differences in MBW outcomes2019 · 26 citations
  4. 4Utility and interpretation of multiple breath washout in children with cystic fibrosis2025 · 3 citations
  5. 5Standards for the care of people with cystic fibrosis (CF); recognising and addressing CF health issues2024 · 85 citations