November 7, 2006Circulation
Hypertrophic Cardiomyopathy Is Predominantly a Disease of Left Ventricular Outflow Tract Obstruction
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Key result
In a cohort of 320 HCM patients, 70% exhibited LV outflow obstruction at rest or with exercise, highlighting the need for routine exercise echocardiography in evaluation.
Why the study?
Does exercise echocardiography identify left ventricular outflow tract obstruction in patients with hypertrophic cardiomyopathy without resting obstruction?
Population
Consecutive patients with hypertrophic cardiomyopathy (HCM)
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Exercise echocardiography may identify obstruction in most HCM patients; challenges nonobstructive predominance but leaves open effects on management and outcomes.
Structured PICO
Does exercise echocardiography identify left ventricular outflow tract obstruction in patients with hypertrophic cardiomyopathy without resting obstruction?
P
Population
Consecutive patients with hypertrophic cardiomyopathy (HCM)
I
Intervention
Exercise echocardiography and Valsalva maneuver
O
Outcome
Prevalence and magnitude of left ventricular (LV) outflow tract obstruction at rest and with physiological exercisesurrogate
Exercise echocardiography reveals that hypertrophic cardiomyopathy is predominantly an obstructive disease, identifying significant outflow gradients in many symptomatic patients without resting obstruction.
Cite This Study
Maron et al. (2006) studied this question. In a cohort of 320 HCM patients, 70% exhibited LV outflow obstruction at rest or with exercise, highlighting the need for routine exercise echocardiography in evaluation.
Topics
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