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March 25, 2026MicroorganismsOpen Access

African Swine Fever: Vaccine Advancement and Major Gaps

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Authors

LWL. WangJSJishu Shi

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Overview

Narrative review summarizes ASF vaccine research gaps and opportunities for effective solutions.

Key Points

  • The aim is to identify advancements and gaps in developing vaccines for African swine fever (ASF).
  • Narrative review of existing vaccine strategies including inactivated, subunit, DNA/mRNA, vectored, and live attenuated virus vaccines.
  • Analysis of ASF vaccine performance and immune response.
  • Identification of knowledge gaps in ASF biology and vaccine safety standards.
  • Inactivated vaccines failed to provide robust protection due to poor immune activation.
  • Subunit vaccines showed limited success in inducing sterile immunity.
  • Live attenuated virus vaccines demonstrated the most promise for eliciting durable immune responses.

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/69c37b93b34aaaeb1a67e2aehttps://doi.org/10.3390/microorganisms14030706
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