An annual decline of ≥ 1 mm Hg in SBP and PP was a strong risk factor for a rapid annual kidney function decline in all age strata, independent of baseline BP and comorbidities.

8,636 patients aged 60 and older with at least one blood pressure measurement in 2002 and at least four serum creatinine measurements after 2002, from a primary care registration network.

Baseline blood pressure and change in systolic blood pressure, diastolic blood pressure, and pulse pressure over time.

Slope of the estimated glomerular filtration rate (eGFR) and rapid annual decline of kidney function (defined as ≥ 3 L/min/1.73 m²/year).surrogate