April 3, 2013Heart and VesselsOpen Access

Impact of aging on the clinical outcomes of Japanese patients with coronary artery disease after percutaneous coronary intervention

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Why the study?

Does advanced age (≥75 years) worsen clinical outcomes in Japanese patients with coronary artery disease after percutaneous coronary intervention?

Population

1,214 Japanese patients with coronary artery disease who underwent percutaneous coronary intervention, from…

Comparison

Elderly age (≥75 years, n=260) vs Non-elderly age (<75 years, n=954)

Design

Cohort

Authors

HKHidehiro KanekoInterventional / Structural Cardiology JYJunji YajimaCardiovascular Institute Hospital YOYuji OikawaCardiovascular Institute Hospital

Discussion

Member takes

Implication

Supports closer monitoring of elderly post-PCI patients with low eGFR or reduced LVEF; leaves open whether targeted interventions improve outcomes.

Structured PICO

Does advanced age (≥75 years) worsen clinical outcomes in Japanese patients with coronary artery disease after percutaneous coronary intervention?

Population

1,214 Japanese patients with coronary artery disease who underwent percutaneous coronary intervention (PCI), from a single-hospital cohort (Shinken Database).

Intervention

Elderly age (≥75 years, n=260)

Comparator

Non-elderly age (<75 years, n=954)

Outcome

Major adverse cardiac event (MACE), defined as a composite of all-cause death, myocardial infarction (MI), and target lesion revascularizationcomposite

Elderly Japanese patients undergoing PCI have worse clinical outcomes than non-elderly patients, with left ventricular and renal dysfunction synergistically contributing to adverse outcomes.

Cite This Study

Kaneko et al. (2013) studied this question.

synapsesocial.com/papers/6a0fb61c57bfcc72645fb501 https://doi.org/10.1007/s00380-013-0339-9

Topics

HFrEF treatment Coronary artery disease Percutaneous coronary intervention Heart failure

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Implication

Supports closer monitoring of elderly post-PCI patients with low eGFR or reduced LVEF; leaves open whether targeted interventions improve outcomes.

Impact of aging on the clinical outcomes of Japanese patients with coronary artery disease after percutaneous coronary intervention

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Impact of aging on the clinical outcomes of Japanese patients with coronary artery disease after percutaneous coronary intervention

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider