Why the study?
Does cardiomegaly alter the basic architecture and contractile properties of the adult rat ventricular myocardium?
Does cardiomegaly alter the basic architecture and contractile properties of the adult rat ventricular myocardium?
In adult rats, cardiomegaly occurs through the addition of sarcomeres in series and increased cross-sectional area without altering the fundamental contractile or electrical properties of the myocardium.
No takes yet. Share an insight, caveat, or question.
May preserve contractile function in rat cardiomegaly; challenges consensus on inherent detriment but leaves open human translation.
Grimm et al. (1963) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: