Why the study?
Does gamma scintigraphy with indium-111-labeled lymphocytes accurately monitor the reversal of cardiac allograft rejection following salvage immunosuppressive therapy in a canine model?
Population
5 dogs after thoracic heterotopic cardiac transplantation.
Comparison
Gamma scintigraphy after administration of… vs Native hearts or allografts during initial…
Design
Preclinical
Authors
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May allow noninvasive monitoring of rejection reversal in canine allografts; leaves open translation to human transplantation.
Does gamma scintigraphy with indium-111-labeled lymphocytes accurately monitor the reversal of cardiac allograft rejection following salvage immunosuppressive therapy in a canine model?
Gamma scintigraphy with indium-111-labeled lymphocytes can noninvasively detect the reversal of cardiac allograft rejection following salvage immunosuppressive therapy in a canine model.
Rosenbloom et al. (1988) studied this question.
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