Why the study?
Does cardiac contractility modulation reduce all-cause mortality and hospitalizations in patients with heart failure?
Population
641 participants with heart failure from 3 randomized controlled trials
Comparison
Cardiac contractility modulation (CCM) vs Sham treatment or usual care
Design
Meta-analysis
Authors
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CCM does not reduce mortality or hospitalizations in HF; confirms neutral effect on primary endpoints.
Does cardiac contractility modulation reduce all-cause mortality and hospitalizations in patients with heart failure?
Cardiac contractility modulation does not significantly improve all-cause mortality or hospitalizations in heart failure patients, though it appears safe.
Kwong et al. (2012) studied this question.
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