Why the study?
Gender differences have been noted in studies linking blood pressure to dementia, but how gender modifies this relationship remains unclear.
Does gender modify the relationship between high blood pressure and the risk of dementia?
Comparison
High blood pressure or hypertension vs normal blood pressure stratified by gender
Design
Systematic review conducted according to PRISMA guidelines
Authors
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May support sex-specific midlife BP monitoring in women; extends observational data but leaves causal effects open for RCTs.
Does gender modify the relationship between high blood pressure and the risk of dementia?
Higher midlife systolic blood pressure appears to be associated with a greater risk of all-cause dementia in women compared to men, highlighting the need for gender-specific investigations.
Blanken et al. (2020) studied this question.
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