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Does evaluation of flow volume and flow patterns using VENC-MRI predict aortic enlargement in patients with chronic aortic dissections?
Does evaluation of flow volume and flow patterns using VENC-MRI predict aortic enlargement in patients with chronic aortic dissections?
VENC-MRI evaluation of flow patterns in the patent false lumen of chronic aortic dissections can predict the rate of aortic enlargement, with primarily antegrade flow associated with the greatest enlargement.
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May support VENC-MRI flow assessment to stratify enlargement risk in chronic dissection; leaves open prospective validation and therapeutic impact.
In 21 patients with chronic aortic dissections and proven patent false lumens, the flow volume and flow patterns in the patent false lumens was evaluated using velocity-encoded cine magnetic resonance imaging (VENC-MRI) and the relationship between the flow characteristics and aortic enlargement was retrospectively examined. Flow patterns in the false lumen were divided into 3 groups: pattern A with primarily antegrade flow (n=6), pattern R with primarily retrograde flow (n=3), and pattern B with bidirectional flow (n=12). In group A, the rate of flow volume in the false lumen compared to the total flow volume in true and false lumens (%TFV) and the average rate of enlargement of the maximum diameter of the dissected aorta per year (ΔD) were significantly greater than in groups R and B (%TFV: 74.1±0.07 vs 15.2±0.03 vs 11.8±0.04, p<0.01; ΔD: 3.62±0.82 vs 0 vs 0.58±0.15 mm/year, p<0.05, respectively). There was a significant correlation between %TFV and ΔD (r=0.79, p<0.0001). Evaluation of flow volume and flow patterns in the patent false lumen using VENC-MRI may be useful for predicting enlargement of the dissected aorta.
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Inoue et al. (2000) studied this question.
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