Key result
Patients with persistent AF and left atrial dimension >50 mm had a significantly lower dominant frequency (4.542 vs 5.057, p=0.002) and higher organization index (0.322 vs 0.261, p=0.007) in lead V1.
Why the study?
It was unknown whether dominant frequency and organization index derived from frequency domain analysis can indicate left atrial dilatation in patients with AF.
Does left atrial dilatation affect the dominant frequency and organization index on surface electrocardiogram in patients with persistent atrial fibrillation?
Population
100 patients with persistent AF
Comparison
LAD > 50 mm vs LAD <= 50 mm
Design
Observational retrospective single-center propensity score-matched cohort study
Authors
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Larger left atria associate with altered AF electrogram features on ECG; leaves open whether these metrics aid risk stratification or ablation selection.
Cohort (n=100)
No
Does left atrial dilatation affect the dominant frequency and organization index on surface electrocardiogram in patients with persistent atrial fibrillation?
p-value: p=0.002
In patients with persistent atrial fibrillation, larger left atrial size is associated with a lower dominant frequency and higher organization index on surface ECG, indicating that structural remodeling alters atrial electrical properties.
Choi et al. (2020) conducted a cohort in Persistent atrial fibrillation (n=100). Left atrial dimension > 50 mm vs. Left atrial dimension ≤ 50 mm was evaluated on Dominant frequency (DF) and organization index (OI) (p=0.002). Patients with persistent AF and left atrial dimension >50 mm had a significantly lower dominant frequency (4.542 vs 5.057, p=0.002) and higher organization index (0.322 vs 0.261, p=0.007) in lead V1.
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