Why the study?
Does 100% supplemental oxygen reduce peak forearm flow and increase vascular resistance in normal subjects?
Population
Normal subjects
Comparison
100% O2 (supplemental oxygen) vs Room air breathing (RA)
Design
Other
Authors
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May warrant caution with hyperoxia in ischemia; leaves open translation to heart failure.
Does 100% supplemental oxygen reduce peak forearm flow and increase vascular resistance in normal subjects?
Supplemental oxygen reduces peak forearm flow and increases vascular resistance in normal subjects, including under conditions simulating congestive heart failure.
Crawford et al. (1997) studied this question.
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