Why the study?
Does the use of nitrovasodilators affect the risk of upper gastrointestinal bleeding in patients, including those taking nonsteroidal antiinflammatory drugs?
Population
3,353 patients, comprising 1,122 cases admitted to one of four hospitals with bleeding from a peptic lesion…
Comparison
Use of nitrovasodilators, low-dose aspirin… vs Non-use of the respective medications.
Design
Case-control
Authors
Loading...
Hypothesis-generating for nitrovasodilator gastroprotection in NSAID users; prospective trials needed before clinical adoption.
Does the use of nitrovasodilators affect the risk of upper gastrointestinal bleeding in patients, including those taking nonsteroidal antiinflammatory drugs?
The use of nitrovasodilators is independently associated with a decreased risk of upper gastrointestinal bleeding, including a protective effect in patients taking nonsteroidal antiinflammatory drugs.
Lanas et al. (2000) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: