Association between metabolic syndrome and parameters of 24-hour blood pressure ambulatory monitoring
Key result
Metabolic syndrome was associated with higher cardiovascular risk (OR 4.5 and 3.6) and elevated 24-hour pulse pressure (OR 2.3 and 4.7) in hypertensive patients.
Population
136 hypertensive subjects, of both sexes, aged between 29 and 83 years.
Design
Cross-sectional
Authors
Discussion
Loading...
Member takes
Implication
Cross-sectional associations should not change hypertension management; leaves open prospective confirmation of metabolic syndrome effects on ambulatory BP.
Key Points
- To determine the association between metabolic syndrome and 24-hour ambulatory blood pressure monitoring parameters as indicators of cardiovascular risk.
- Evaluated 136 hypertensive adults aged 29 to 83 years of both sexes using 24-hour ambulatory blood pressure monitoring.
- Defined cardiovascular risk criteria based on systolic/diastolic hypertension (≥ 140/90 mmHg), blunted nocturnal dipping, and elevated pulse pressure (> 53 mmHg) across 24-hour, daytime, and nighttime periods.
- Metabolic syndrome was present in 58.1% of participants, dyslipidemia in 88.8%, abdominal obesity in 60.3%, and elevated 24-hour pulse pressure in 54.0%.
- Age-adjusted metabolic syndrome was significantly associated with elevated cardiovascular risk (OR = 4.5 and 3.6), higher 24-hour pulse pressure (OR = 2.3 and 4.7), and increased daytime pulse pressure (OR = 2.2 and 4.6).
Study Design
Type
Cross-Sectional (n=136)
Structured PICO
P
Population
136 hypertensive adults aged 29 to 83 years evaluated for associations between metabolic syndrome and 24-hour blood pressure parameters.
O
Outcome
24-hour blood pressure parameters as a measure of cardiovascular risk (CVR)surrogate
Main Result
Effect estimate: OR 4.5 and 3.6
Metabolic syndrome is highly prevalent in hypertensive patients and is significantly associated with altered 24-hour ambulatory blood pressure parameters, indicating higher cardiovascular risk.
Cite This Study
Felisbino-Mendes et al. (2011) conducted a cross-sectional in Hypertension (n=136). Metabolic syndrome vs. Absence of metabolic syndrome was evaluated on Higher cardiovascular risk (CVR) (OR 4.5 and 3.6). Metabolic syndrome was associated with higher cardiovascular risk (OR 4.5 and 3.6) and elevated 24-hour pulse pressure (OR 2.3 and 4.7) in hypertensive patients.