Population
Transgenic mice harboring the bovine homolog, bmyf, under control of the murine sarcoma virus promoter
Design
Preclinical
Authors
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Ectopic bmyf expression risks cardiomyopathy; leaves open safe myf5 targeting for myogenic lineage therapies.
The myf5 gene can initiate myogenic differentiation in vivo, supporting its role in determining cells to the myogenic lineage during embryogenesis.
Santerre et al. (1993) studied this question.
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