Why the study?
Does regional myocardial ischemia alter the series elastic and contractile elements in glycerinated heart muscle fibers of dogs?
Population
Glycerinated heart muscle fibers of dogs
Comparison
Myocardial infarction induced by ligating left… vs Non-ischemic/fresh papillary muscle fibers
Design
Preclinical
Follow-up
3 hours
Authors
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Does not support changes in human MI management; leaves open whether ischemia alters elastic elements in clinical myocardium.
Does regional myocardial ischemia alter the series elastic and contractile elements in glycerinated heart muscle fibers of dogs?
Acute myocardial infarction in a dog model leads to increased stiffness of the series elastic element and diminished contractility in glycerinated heart muscle fibers.
Maruyama et al. (1980) studied this question.
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