Key result
Postnatal development in mouse atrium is associated with significant up-regulation of all examined K(+) currents, resulting in a dramatic shortening of the action potential duration.
Authors
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Informs murine atrial maturation models; leaves open translation to human developmental electrophysiology or arrhythmias.
Véronique Trépanier‐Boulay (2004) studied Postnatal development of atrial repolarization. Postnatal development (age) vs. Different age groups (Day-1, Day-7, Day-20, adult) was evaluated on Action potential duration (APD) and voltage-dependent K(+) currents. Postnatal development in mouse atrium is associated with significant up-regulation of all examined K(+) currents, resulting in a dramatic shortening of the action potential duration.
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