Key result
Amiodarone significantly reduced heart rate (P<0.001) and improved clinical signs in 92.9% of dogs with refractory arrhythmias, without significant changes in liver or thyroid parameters.
Why the study?
Does amiodarone reduce heart rate and improve clinical signs in dogs with refractory supraventricular and ventricular arrhythmias?
Observational (n=28)
Does amiodarone reduce heart rate and improve clinical signs in dogs with refractory supraventricular and ventricular arrhythmias?
p-value: p=<0.001
Amiodarone appears to be an effective and safe alternative for treating refractory supraventricular and ventricular arrhythmias in dogs.
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Amiodarone may benefit dogs with refractory arrhythmias; leaves open the need for randomized trials to confirm efficacy and safety.
Pedro et al. (2011) conducted an observational in Refractory supraventricular and ventricular arrhythmias (n=28). Amiodarone was evaluated on Heart rate reduction and improvement in arrhythmia severity and clinical signs (p=<0.001). Amiodarone significantly reduced heart rate (P<0.001) and improved clinical signs in 92.9% of dogs with refractory arrhythmias, without significant changes in liver or thyroid parameters.
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