Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 1, 1995Hypertension

Angiotensin II Induces Cardiac Phenotypic Modulation and Remodeling In Vivo in Rats

View Full Paper
Ask AI
Bookmark
Share

Authors

SKShokei KimOtsuka (Japan)KOKensuke OhtaSumitomo Chemical (Japan)AHAkinori HamaguchiKyowa Kirin (Japan)

Discussion

Loading...

Member takes

Overview

Ang II may drive cardiac remodeling independent of BP in rats; leaves open translation to human hypertrophy or therapy.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Kim et al. (1995) studied this question.

synapsesocial.com/papers/6a21603dbaff55cd04030a48https://doi.org/10.1161/01.hyp.25.6.1252
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype.1993 · 1,429 citations
  2. 2Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells1990 · 356 citations
  3. 3Converting Enzyme Inhibition Specifically Prevents the Development and Induces Regression of Cardiac Hypertrophy in Rats1989 · 336 citations
  4. 4Regulation of fibrillar collagen types I and III and basement membrane type IV collagen gene expression in pressure overloaded rat myocardium.1990 · 232 citations
  5. 5Antithetical accumulation of myosin heavy chain but not alpha-actin mRNA isoforms during early stages of pressure-overload-induced rat cardiac hypertrophy.1993 · 44 citations