Key result
Atrial lead placement at the lower atrial septum significantly shortened the As-Vs interval compared to right atrial appendage pacing (134 ± 44 ms vs. 194 ± 52 ms, P<0.001).
Why the study?
Does atrial lead placement at the lower atrial septum reduce AV intervals compared to the right atrial appendage in patients receiving a dual-chamber pacemaker or implantable cardioverter defibrillator?
Population
57 patients receiving a dual-chamber pacemaker or implantable cardioverter defibrillator
Comparison
Atrial lead placement at the lower atrial septum vs Atrial lead placement at the right atrial…
Design
RCT, random order
Follow-up
acute (during device implant)
Authors
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May reduce unnecessary RV pacing in dual-chamber devices; extends RCT evidence for lower septal atrial leads.
RCT (n=57)
Random order
No
Does atrial lead placement at the lower atrial septum reduce AV intervals compared to the right atrial appendage in patients receiving a dual-chamber pacemaker or implantable cardioverter defibrillator?
Absolute Event Rate: 134% vs 194%
p-value: p=<0.001
Pacing from the lower atrial septum significantly shortens AV intervals compared to the right atrial appendage, offering a potential strategy to reduce unnecessary right ventricular pacing.
Acosta et al. (2012) conducted an RCT in Patients receiving a dual-chamber pacemaker or implantable cardioverter defibrillator (n=57). Atrial lead placement at the lower atrial septum (LAS) vs. Right atrial appendage (RAA) pacing was evaluated on As-Vs interval (p=<0.001). Atrial lead placement at the lower atrial septum significantly shortened the As-Vs interval compared to right atrial appendage pacing (134 ± 44 ms vs. 194 ± 52 ms, P<0.001).
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