Key result
The minor allele G of SNP rs894379 in the CNTLN gene was associated with increased left ventricular mass in hypertensive individuals (β = 2.46, P = 0.0026).
Why the study?
Is the SNP rs894379 associated with increased left ventricular mass in hypertensive individuals?
Observational (n=1,859)
Yes
Is the SNP rs894379 associated with increased left ventricular mass in hypertensive individuals?
Effect estimate: β = 2.46
p-value: p=0.0026
A novel genetic variant (rs894379) on chromosome 9p22 is associated with increased left ventricular mass in hypertensive patients, improving understanding of the genetic determinants of this trait.
No takes yet. Share an insight, caveat, or question.
Should not change hypertension management; hypothesis-generating for CNTLN variants in LV remodeling.
Menni et al. (2012) conducted an observational in Hypertension (n=1,859). SNP rs894379 minor allele G was evaluated on Left ventricular mass (LVM) (β = 2.46, p=0.0026). The minor allele G of SNP rs894379 in the CNTLN gene was associated with increased left ventricular mass in hypertensive individuals (β = 2.46, P = 0.0026).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: