Population
Adenovirus tripartite leader RNA (in vitro model)
Design
Preclinical
Authors
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May guide adenoviral vector optimization; leaves open functional validation in mammalian systems.
The secondary structure of the adenovirus tripartite leader RNA features a single-stranded first segment and base-paired subsequent segments, which may explain its ability to enhance translation independently of the cap binding protein complex.
Zhang et al. (1989) studied this question.
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