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Calcium phosphate bone cements modified with 10 wt% α-ketoglutarate polyester microspheres exhibit optimal osteogenic capacity and promote osteoporotic bone defect repair. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 2025Journal of Materials Chemistry B14 citationsOpen Access

Calcium phosphate bone cements with α-ketoglutarate polyester microspheres promote osteoporotic bone defect repair

ZKZhengyang KangThird Affiliated Hospital of Southern Medical University HYHui YangBeijing Tongren Hospital XLXinzhi LiangThird Affiliated Hospital of Southern Medical University

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Abstract

signaling pathway. Notably, the addition of 10 wt% α-KG polyester microspheres resulted in the optimal osteogenic capacity for CPC/α-KG. In conclusion, the modified α-KG composites show potential as effective candidates for bone defect repair and regeneration.

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