Calcium phosphate bone cements with α-ketoglutarate polyester microspheres promote osteoporotic bone defect repair

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Calcium phosphate bone cements modified with 10 wt% α-ketoglutarate polyester microspheres exhibit optimal osteogenic capacity and promote osteoporotic bone defect repair. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Zhengyang Kang; Hui Yang; Xinzhi Liang; Bin Wu; Dequan Wang; Tingliang Xiong; Luhui Zhang; Denghui Xie

doi:10.1039/d5tb00380f

January 1, 2025Journal of Materials Chemistry BOpen Access

Calcium phosphate bone cements with α-ketoglutarate polyester microspheres promote osteoporotic bone defect repair

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Abstract

signaling pathway. Notably, the addition of 10 wt% α-KG polyester microspheres resulted in the optimal osteogenic capacity for CPC/α-KG. In conclusion, the modified α-KG composites show potential as effective candidates for bone defect repair and regeneration.

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Kang et al. (2025) studied this question.

synapsesocial.com/papers/6a2434f6ae2541b4f5adb887 https://doi.org/10.1039/d5tb00380f

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Calcium phosphate bone cements with α-ketoglutarate polyester microspheres promote osteoporotic bone defect repair

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Abstract

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Calcium phosphate bone cements with α-ketoglutarate polyester microspheres promote osteoporotic bone defect repair

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Abstract

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