Key result
Factor V Leiden mutation was not associated with an increased risk of left ventricular thrombus formation in patients with acute myocardial infarction (mutation prevalence 9% with thrombus vs 7.7% without).
Why the study?
Does the Factor V Leiden mutation increase the risk of left ventricular thrombus formation in patients with acute myocardial infarction?
Population
135 consecutive patients with first anterior acute myocardial infarction and 95 healthy age and sex-matched…
Comparison
Presence of Factor V Leiden mutation vs Absence of Factor V Leiden mutation
Design
Cohort
Follow-up
30 days
Authors
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Factor V Leiden does not predict post-AMI LV thrombus; leaves open confirmation in larger prospective cohorts.
Observational (n=230)
Does the Factor V Leiden mutation increase the risk of left ventricular thrombus formation in patients with acute myocardial infarction?
The Factor V Leiden mutation is not a significant risk factor for the formation of left ventricular thrombus following an acute myocardial infarction.
ÇELIK et al. (2001) conducted an observational in Acute myocardial infarction (n=230). Factor V Leiden mutation vs. Absence of Factor V Leiden mutation was evaluated on Left ventricular thrombus formation. Factor V Leiden mutation was not associated with an increased risk of left ventricular thrombus formation in patients with acute myocardial infarction (mutation prevalence 9% with thrombus vs 7.7% without).