Why the study?
What are the pretransplant predictors of new-onset heart failure after liver transplantation?
Population
970 liver transplantation (LT) recipients between January 2000 and December 2010
Design
Cohort
Follow-up
5.3 ± 3.4 years
Key result
In 970 liver transplant recipients, 10.1% developed new-onset heart failure over 5.3 years, with pretransplant diastolic dysfunction, diabetes, and hypertension identified as predictors.
Authors
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Supports risk stratification in liver transplant candidates; leaves open whether modifying diastolic dysfunction, diabetes, or hypertension reduces heart failure incidence.
Cohort (n=970)
What are the pretransplant predictors of new-onset heart failure after liver transplantation?
Pretransplant risk factors, including grade 3 diastolic dysfunction, diabetes, and specific hemodynamic parameters, are important predictors of post-liver transplant heart failure, which independently predicts mortality.
Qureshi et al. (2013) conducted a cohort in Liver transplantation (n=970). Pretransplant clinical, hemodynamic, and echocardiographic variables vs. Absence of these variables was evaluated on Post-LT heart failure (systolic, diastolic, or mixed). In 970 liver transplant recipients, 10.1% developed new-onset heart failure over 5.3 years, with pretransplant diastolic dysfunction, diabetes, and hypertension identified as predictors.
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