Key result
Baseline blood pressure was not associated with incident dementia, but incident dementia cases exhibited a greater decline in systolic blood pressure (p=0.02) and pulse pressure (p=0.04).
Why the study?
Is baseline blood pressure or blood pressure decline associated with incident dementia in the very old?
Population
102 individuals aged 85, 90 or ≥ 95 years from a population-based cohort
Design
Cohort
Follow-up
5 years
Authors
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BP decline should not alter management in the very old; leaves open causality and need for prospective studies.
Cohort (n=102)
Is baseline blood pressure or blood pressure decline associated with incident dementia in the very old?
p-value: p=0.02
Molander et al. (2010) conducted a cohort in Dementia (n=102). Blood pressure was evaluated on Incident dementia and decline in MMSE scores (p=0.02). Baseline blood pressure was not associated with incident dementia, but incident dementia cases exhibited a greater decline in systolic blood pressure (p=0.02) and pulse pressure (p=0.04).
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