Key result
Compared to a normotensive model, simulated mild and moderate hypertension increased average left ventricular fiber stress by 21% and 36%, and circulatory work by 18% and 43%, respectively.
Coupled finite element and circulatory models demonstrate that even mild hypertension significantly increases left ventricular fiber stress and circulatory work.
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May increase LV fiber stress even in mild hypertension; hypothesis-generating from simulations and requires clinical validation.
Veress et al. (2013) studied Hypertension. Mild and moderate hypertension simulation vs. Normal left ventricle under normotensive aortic loading was evaluated on Average fiber stress levels and circulatory work. Compared to a normotensive model, simulated mild and moderate hypertension increased average left ventricular fiber stress by 21% and 36%, and circulatory work by 18% and 43%, respectively.
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