Why the study?
Does diltiazem reduce acute hyperdynamic responses in patients undergoing electroconvulsive therapy?
Population
18 patients undergoing electroconvulsive therapy (ECT)
Comparison
Diltiazem 10 mg vs Placebo
Design
RCT, randomized cross-over study design, double-blinded, placebo-controlled
Authors
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Reserve diltiazem for high-risk ECT patients; extends RCT evidence on hemodynamic blunting.
Does diltiazem reduce acute hyperdynamic responses in patients undergoing electroconvulsive therapy?
While diltiazem effectively blunts tachycardia and hypertension during ECT, it shortens seizure duration, suggesting its use should be limited to high-risk patients.
Wajima et al. (2001) studied this question.
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