Why the study?
Does perindopril compared to nifedipine improve albumin excretion rate, blood pressure, and glomerular filtration rate in diabetic patients with microalbuminuria?
Population
50 diabetic patients with persistent microalbuminuria
Comparison
Perindopril 2-8 mg daily for 12 months vs Nifedipine 20-80 mg daily for 12 months
Design
RCT, Randomised separately according to whether they were hypertensive or…
Follow-up
12 months
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Supports either agent for BP and albuminuria control in diabetic microalbuminuria; confirms comparable efficacy in this population.
Does perindopril compared to nifedipine improve albumin excretion rate, blood pressure, and glomerular filtration rate in diabetic patients with microalbuminuria?
Perindopril and nifedipine demonstrate comparable efficacy in managing blood pressure and urinary albumin excretion in diabetic patients with microalbuminuria.
A 1991 study studied this question.
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