Why the study?
Does benazepril reduce overnight microalbuminuria more effectively than nicardipine in normotensive and hypertensive diabetic patients?
Population
103 diabetic patients (57 normotensive and 46 hypertensive) with microalbuminuria
Comparison
Benazepril 10 mg oral once daily for 6 months vs Nicardipine 20 mg oral twice daily for 6 months
Design
RCT, Stratified on the basis of the presence or absence of arterial…
Follow-up
6 months
Authors
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Benazepril may be preferred over nicardipine for microalbuminuria reduction in diabetes; confirms ACEI renoprotection independent of BP lowering.
Does benazepril reduce overnight microalbuminuria more effectively than nicardipine in normotensive and hypertensive diabetic patients?
Benazepril is more effective than nicardipine in reducing overnight microalbuminuria in diabetic patients, independent of its antihypertensive properties.
Cesaris et al. (1996) studied this question.
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