Why the study?
Does intravenous nicardipine improve renal hemodynamics in hypertensive type II diabetic patients with nephropathy?
Population
20 patients including 8 with essential hypertension, 6 hypertensive type II diabetics with mild-to-moderate…
Comparison
Intravenous nicardipine hydrochloride (0.5 mg). vs Saline placebo.
Design
RCT, Random order (crossover design)
Follow-up
30 minutes
Authors
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Nicardipine may improve renal hemodynamics in mild-to-moderate diabetic nephropathy; extends RCT data on calcium-channel blockade but leaves hard outcomes untested.
Does intravenous nicardipine improve renal hemodynamics in hypertensive type II diabetic patients with nephropathy?
Intravenous nicardipine improves renal hemodynamics in hypertensive type II diabetics with mild-to-moderate nephropathy, but this effect is lost in severe nephropathy.
Baba et al. (1986) studied this question.
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