Population
In vitro cell culture models and a transgenic mouse model overexpressing ECFP/ANG II
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Review
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Intracellular Ang II may contribute to hypertension; leaves open whether it represents a viable human therapeutic target.
Intracellular angiotensin II exerts diverse pleiotropic effects and is directly linked to high blood pressure in transgenic models, highlighting potential alternative targets for renin-angiotensin system modulation.
Cook et al. (2011) studied this question.
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