Why the study?
Does intravenous fenoldopam improve hemodynamics and blood pressure in patients with severe hypertension or heart failure compared to sodium nitroprusside?
Population
Normal volunteers, patients with hypertension, and patients with moderate to severe congestive heart failure
Comparison
Intravenous fenoldopam vs Sodium nitroprusside
Design
Review
Authors
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May support fenoldopam as alternative in severe hypertension or HF; leaves open confirmation in contemporary RCTs.
Does intravenous fenoldopam improve hemodynamics and blood pressure in patients with severe hypertension or heart failure compared to sodium nitroprusside?
Intravenous fenoldopam is an efficacious alternative to sodium nitroprusside for treating severe hypertension and acute congestive heart failure, offering favorable renal and systemic hemodynamic effects.
Holcslaw et al. (1990) studied this question.
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